Vitamin B12
Enjoy Vitamin B12
B cobalamin
Vitamin B12 may be decreased in those who eat a vegan diet. Increased requirements occur in HIV/AIDS and in those with rapid red blood cell breakdownVitamin such as with PKD. B12 is a water soluble B vitamin that is oftentimes low in PKD/PLD. Get a B12 level to assure the reason for any existing anemia. If you are a vegan, you will need to take supplemental B12.The only vegan food sources have been fortified with B12. The PKD diet was evaluated by several renal research dietitians and found to be low in B12. Daily dose of this vitamin might be useful if you are vegan. Then after taking B12 get a serum B12 to evaluate your level. As this is a water soluble there is very little danger of over dosing. Excess will be eliminated in the urine.
Food Sources Vitamin B12
Vitamin B-12 is mostly available only in animal foods: meat, fish, poultry, eggs, and dairy products. These are animal products all can increase protein spillage in the urine. Do not take any animal products. You can also get Vitamin B12 nutrient in some nutritional yeasts, as well as from fortified cereals and soy milk, all harmful to PKD. Yeast raises uric acid levels, already high in PKD. Fortified cereals contain many other harmful chemicals. These are prepared foods, processed foods. And soy is harmful for cystic organs. Vegans need to take a vitamin-B supplement daily.
The main syndrome of vitamin B12 deficiency is pernicious anemia.
When cyanocobalamin enters your body from B12 supplement, it is converted into either methylcobalamin or adenosylcobalamin, which are the two active forms of vitamin B12 in humans. Unlike cyanocobalamin, methylcobalamin is a naturally occurring form of vitamin B12 that can be obtained through supplements, as well as food sources like fish, meat, eggs and milk. Cyanocobalamin is a synthetic form of vitamin B12 found only in supplements, while methylcobalamin is a naturally occurring form that you can get through either food sources or supplements.
One step in that process is changing cyanocobalamin to hydroxocobalamin. The body does this by wrenching away a cyanide molecule from cyanocobalamin, and letting it loose in the body. In fact, when a person is poisoned with cyanide, as sometimes happens following smoke inhalation, and they are rushed to the emergency room, what do they give them to remove the cyanide? Hydroxocobalamin -- a cyanide-free form of vitamin b12 -- which readily binds with the cyanide, becoming cyanocobalamin, which sequesters the cyanide, putting it into a less toxic form that can be more readily eliminated from the body via the lungs and kidneys.
