POLYCYCTIC KIDNEY DISEASE DIET

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PLD

92% PLD have no symptoms.

These lucky 92% have polycystic liver disease but they do not need to be concerned about it. Without experiencing any symptoms it is very likely that there is no need for treatment. Only a few of us, about 8%, develop severe PLD Polycystic Liver Disease. Polycystic livers can go from a texture similar to a smooth peach to that of resembling a bumpy fluid filled raspberry. Polycystic liver disease is inherited, either with kidney cysts ADPKD or without, ADPLD.

At least 90% of ADPKD individuals have liver cysts. It has been postulated that perhaps 100% of individuals with ADPKD have some liver cysts especially if they can be imaged with a fine slice MRI machine. 100 CRISP study participants, were imaged showing that most, if not all, had liver cysts. However, only a very small percentage go on to develop difficulties related to their liver cysts.

An individual in their 20's or 30's having only 2-3 liver cysts, will rarely develop massive symptoms from their polycystic liver. Interestingly a greater percentage of females have difficulties, almost 8:1. Several studies have looked at liver cyst growth in relation to pregnancy and estrogen. Hormones, caffeine, and liver toxins cause liver cyst growth. Women who went on to use HRT hormonal replacement therapy following menopause experienced greater cystic liver growth. Liver cysts can occur as fine small grape like clusters or they can occur as very large cysts or a mixture of both types. In general, liver cysts are a disease of aging. If we live long enough, eventually all develop a liver cyst. If someone has one large liver cysts or even up to three liver cysts, these are simple cysts and not necessarily autosomal dominant polycystic liver disease or autosomal dominant polycystic kidney disease with liver cysts. The definition of PLD is 20 or more liver cysts.

Hormones, particularly estrogen, rapidly spurs the growth of liver cysts. Caffeine, bleach, plastic, ammonia, dairy, false estrogens, soy and flaxseed also increase liver cyst pain and growth. As the liver becomes filled with cysts, the metabolism of estrogen within the liver diminishes. A saliva hormonal profile test can document these changes, but many are reluctant to have costly lab tests performed when it seemingly does not alter the treatment of PLD. Listen to a lecture on PLD.

How do Liver Cysts Develop?

Included among liver cells are hepatocytes and cholangiocytes. Liver cysts arise only from cholangiocytes cells, yet cholangiocytes make up only 3% of all liver cells. These cholangiocytes are very important in that they produce 40% of the bile. Hepatocytes, the other liver cells, make up 80-90% of the total liver tissue. Cholangiocytes have somatostatin receptors on their exterior cell surface. The interior of liver cysts contain cyclic AMP. Cyclic AMP is elevated in the interior of all cyst cells. Exciting results were published by the Mayo Clinic in the GastroEnterology Journal. Animal studies using Octreotide dramatically decreased both liver and kidney cyst growth. Octreotide is a somatostatin analogue. It stimulates somatostatin receptors and this decreases cyclic AMP within the cyst. Decreasing cyclic AMP diminishes cyst growth. Researchers are hopeful that clinical trials with Octreotide will prove useful in diminishing liver cysts for polycystic liver disease. Sometimes we might experience a prolonged bleeding time or a rise in billirubin, but these are scarce events. News received from time to time, is it is a rare event for a cystic liver to fail. Yet as a polycystic liver enlarges it will gradually slow down in performing some of its processes. PLD forms multiple cysts throughout the liver. Normal non-cystic liver tissue re-grows attempting to displace the cystic liver. The liver is the only human organ capable of regeneration. This regeneration can create a massively growing cystic liver.

If you have PLD, consider taking a survey.

This is a short survey compiled by one of our members with PLD. She is a university student looking to learn more about PLD.

- select PLD article - BOOK PLD diet liver iTunes BOOK PLD Diet Liver pdf BOOK PLD Diet Liver Kindle FREE podcast 11. An Integrative TAKE a PLD Survey IMAGE PLD liver IMAGE PLD person PLD diet LISTS PLD avoid Foods LISTS PLD avoid Herbs LISTS PLD avoid also LISTS PLD avoid xenoestrogens LISTS PLD symptoms PLD LECTURE Dr. Torres listen PLD LECTURE Dr. Perrone part 1 PLD LECTURE Dr. Perrone part 2 PLD LECTURE Dr. Somlo PLD LECTURE Dr. Marie Hogan movie PLD LECTURE Dr. Marie Hogan PLD ELECTRON microscope, hormone receptors PLD LIVERi nvolvement PLD DIAGNOSIS PLD ADPLD cysts PLD NETHERLANDS website PLD GENE PLD CRISP liver cysts CRISP PLD Morphology liver cysts PLD in ADPLD PLD without kidney cysts ADPLD Mayo Clinic PLD SYMPTOM LIST PLD SYMPTOM pain PLD SYMPTOM electron microscope, hormone receptors PLD SYMPTOM Liver Resection PLD SYMPTOM Analysis PLD SYMPTOM lead transplant PLD SYMPTOM compression PLD SYMPTOM no kidney cysts PLD SYMPTOM cardiac compression PLD SYMPTOM pericardial effusion PLD SYMPTOM HVOO PLD SYMPTOM hvoo2004 PLD SYMPTOM budd-chiari PLD SYMPTOM budd-chiari PLD SYMPTOM budd-chiari liver tx PLD SYMPTOM hepatic outlet PLD SYMPTOM Liver Resection PLD SYMPTOM Analysis PLD SYMPTOM Phytoestrogen PLD SYMPTOM Soy PLD SYMPTOM HVOO PLD SYMPTOM hvoo2004 TREATMENT Resection Mayo TREATMENT Resection Mayo Synopsis TREATMENT Resection Mayo Dr. Nagorney Bio TREATMENT Resection Mayo Dr. Nagorney 1995 TREATMENT Resection China TREATMENT Mini invasive TREATMENT Alcohol Ablation TREATMENT Hepatic ablation TREATMENT Surgical manage TREATMENT TAE TREATMENT dillemma RESEARCH Octreotide PLD RESEARCH Lanreotide RESEARCH Lanreotide RESEARCH Hepatic cystogenesis SCLEROTHERAPY NOT definitive SCLEROTHERAPY Glue SCLEROTHERAPY Laporoscopic
SCLEROTHERAPY aspiration SCELEROTHERAPY Radiography SCLEROTHERAPY Laporoscopic SCLEROTHERAPY SCLEROTHERAPY LaporoscopicÍ SCLEROTHERAPY Ethanol SCLEROTHERAPY Sclerotherapy HVOO Veno-occlusive Disease HVOO Budd-Chiari HVOO Radical surgery HVOO inferior caval vein HVOO management HVOO Portosystemic Shunt SIROLIMUS FDA Alert SIROLIMUS Liver Transplants SIROLIMUS FDA Transplant SIROLIMUS FDA alert SIROLIMUS renal function SIROLIMUS transplant rejection SIROLIMUS Hepatotoxicity SIROLIMUS Reduces PLD SIROLIMUS Reduces PLD SIROLIMUS PKD rat model SIROLIMUS New therapies SIROLIMUS Inhibition of mTOR SIROLIMUS Trial Netherlands SIROLIMUS Trial Mayo Clinic SIROLIMUS Trial Mario Negri Inst Italy SIROLIMUS Trial Manzoni Hosp Italy

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We are  sharing our experiences with PLD Diet, an adjunct diet to consider  trying to complement a physician's prescribed medical therapy. Think  about testing this only with your doctor's prior knowledge, who can  adjust it, according to your own uniqueness by adding to your current  treatment.

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