Tylenol
Avoid TylenolŪ
acetaminophen
paracetamol
Tylenol, acetaminophen, paracetamol are all names for the same drug. It remains the most common medication used and the number one cause of acute liver failure. The FDA has gone so far as to issue a box warning
"highlighting the potential for severe liver injury and a Warning highlighting the potential for allergic reactions (e.g., swelling of the face, mouth, and throat, difficulty breathing, itching, or rash) are being added to the label of all prescription drug products that contain acetaminophen."
The difficulty in taking TylenolŪ, acetaminophen, paracetamol, for a long period of time (greater than 1 tablet every 3 months) is that kidney damaging effects are cumulative, gathered over an entire lifetime. Liver failure can occur even when taken in therapeutic doses. A prospective study out of Australia showed the long term use of tylenol caused kidney failure in individuals without any prior kidney disease. When tylenol is combined even with the smallest amount of alcohol this increases by 123% your chances for developing kidney damage. That is the reason most packaging information warns people who have three or more drinks a day to stay away from acetaminophen. Tylenol elevated liver enzymes in healthy adults.
Many kidney doctors caution PKD'rs against using aspirin, paracetamol, tylenol, phenacetin, non-steroidal anti-inflammatory drugs (NSAIDs), or other prescription or over-the-counter medications that impair kidney function. Avoid tylenol, paracetamol, acetaminophen as prolonged use can cause kidney decline and elevation of liver enzymes.
Some PKD'rs use anti-inflammatory foods to relieve pain:
lemon juice for headaches and daily minor kidney and liver aches
cherries for wrist and joint pain
papaya and pineapple are strong anti-inflammatories
useful for ↓ back pain
papaya contains anti-inflammatory papain
pineapple contains anti-inflammatory bromelain
A 2017 conference showed tylenol to cause liver toxicity.