Among the many symptoms of PLD, one early symptom is the appearance of a huge protruding, enlarging liver. It is possible for a PLD cystic liver to grow to 40 pounds exerting a constant slow direct pressure against our internal organs. We often appear as if we have a huge beer belly or might be mistaken as someone who is pregnant.
Other symptoms can include bloating, breathlessness, malnourishment, pain, and a huge protruding liver. As our liver continues to enlarge this pressure can abutt our heart, our spleen, major blood vessels, and even deforming and breaking bones.
PLD'rs are a very stoic group oftentimes waiting until a low level of chronic pain exists before seeking help. Once the pain becomes chronic, relief may come in the form of opioids, such as fentanyl patches or Vicodin. These pain relievers, allow us to function. There is a procedure called a splanchnic denervation. This can be done laparoscopically. It is available at centers throughout the world.
The most common reported PLD symptom is pain and that's what gets us to the doctor. Other symptoms are bloating, distension, and early satiety all from an ever growing polycystic liver. In a study of PLD'rs: