↓ Cysts

The ability to diminish cyst growth lessens symptoms from ADPKD, ADPLD, and improves cystic organ functioning. To accomplish this without medications, some are trying diet, reducing animal proteins, assuring alkalinity is maintained either by diet or supplementing with alkalizers, drinking 3 liters of water, reducing salt intake, avoiding stimulants that trigger cyclic AMP such as caffeine, tea, green tea, coffee, chocolate, de-caf drinks, maté tea, kola nut, and more.

Working with nephrologists some are supplementing with alkalizers such as potassium or sodium citrate. Baking soda or sodium bicarbonate is to be avoided with PKD. Due to the nature of PKD, taking sodium bicarbonate will lead to increased kidney stone formation. We with PKD are prone to kidney stone formation. This is partly from higher urinary uric acid levels, higher urinary calcium levels, and acidic producing cystic kidneys. Avoid adding inexpensive sodium bicarbonate to the mix, the carbonate ion flies off and hooks up with the calcium ion joining and producing calcium carbonate, one of the most common kidney stones formed by PKD'rs. Whereas with citrate salts such as sodium citrate and potassium citrate and to a lesser extent calcium citrate, the citrate molecule flies off and is utilized as energy for the kidney. Citrate salts are inexpensive supplements that may have the potential to reduce cyst growth and definitely prevent future kidney stone formation.

Anxiously we are awaiting completion of clinical trials with a few possible medications to ↓ cyst growth:
angiotensin receptor blockers, ACE inhibitors
octreotide, somatostatin, pasireotide, lanreotide
pioglitazone, metformin
sirolimus, rapamycin, everolimus, mTor inhibitors
tolvaptan, vasopressin receptor antagonists
and there are also many modifiable factors.

What Makes Cysts Grow?

Try the following to ↓ cysts, provided you are not restricted from trying any of these.

  • ↓ stress (adrenaline ↑ cyst growth)

  • Avoid any inflammation (surgery)

  • Eat a vegetarian diet

  • ↑ potassium rich foods (↑ fruits & veg) ↑ kidney functioning

  • ↓ sodium diet

  • ↓ caffeine and chocolate

  • Caffeine in chocolate, cola, and coffee enhances the action of cAMP by inhibiting its breakdown, resulting in more circulating cAMP, which increases cyst growth creating more cysts, increasing organ size and increasing symptoms.

  • Current treatment of PKD include blood pressure control, a low salt diet, regulated increased fluid intake, avoiding caffeine and methylxanthines.

  • Increase water to 4 liters/day

  • We are  sharing our experiences with PKD/PLD Diet, an adjunct diet envisioning it complementing a physician's prescribed medical therapy. Consider testing this with your doctor's prior knowledge, who can  adjust it according to your own uniqueness by adding it to your current  treatment.

    Medical Disclaimer