Soy



References

(1). Rackis, et al., ibid., p. 22; "Evaluation of the Health Aspects of Soy Protein Isolates as Food Ingredients", prepared for FDA by Life Sciences Research Office, Federation of American Societies for Experimental Biology (9650 Rockville Pike, Bethesda, MD 20014), USA, Contract No. FDA 223-75-2004, 1979.


(2). See www/truthinlabeling.org.

(3). See www/unitedsoybean.org.

(4). These are listed in www.soyonlineservice.co.nz.

(5). Wall Street Journal, October 27, 1995.

(6). Urquhart, John, "A Health Food Hits Big Time", Wall Street Journal, August 3, 1999, p. B1

(7). Natural Medicine News (L & H Vitamins, 32-33 47th Avenue, Long Island City, NY 11101), USA, January/February 2000, p. 8.
(8). Harras, Angela (ed.), Cancer Rates and Risks, National Institutes of Health, National Cancer Institute, 1996, 4th edition.
(9). Searle, Charles E. (ed.), Chemical Carcinogens, ACS Monograph 173, American Chemical Society, Washington, DC, 1976.

(10). Ishizuki, Y. et al., "The effects on the thyroid gland of soybeans administered experimentally in healthy subjects", Nippon Naibunpi Gakkai Zasshi (1991) 767:622-629.

(11). Cassidy, A. et al., "Biological Effects of a Diet of Soy Protein Rich in Isoflavones on the Menstrual Cycle of Premenopausal Women", American Journal of Clinical Nutrition (1994) 60:333-340.

(12). Bulletin de L'Office Fédéral de la Santé Publique, no. 28, July 20, 1992.

(13). Setchell, K.D. et al., "Isoflavone content of infant formulas and the metabolic fate of these early phytoestrogens in early life", American Journal of Clinical Nutrition, December 1998 Supplement, 1453S-1461S.

(14). Irvine, C. et al., "The Potential Adverse Effects of Soybean Phytoestrogens in Infant Feeding", New Zealand Medical Journal May 24, 1995, p. 318.

 
 

Soy Articles

(Thyroid) Goitrogenic and estrogenic activity of soy isoflavones. 2002  Include iodine deficiency but may also include additional soy components, other defects of hormone synthesis, or additional goitrogenic dietary factors. Although safety testing of natural products, including soy products, is not required, the possibility that widely consumed soy products may cause harm in the human population via either or both estrogenic and goitrogenic activities is of concern. soythroid.pdf

http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=12060828


Low-Normal Thyroid Function Linked to Cardiac Death 2008

TRONDHEIM, Norway -- Women with thyroid function at the low end of normal appear to be at significantly increased risk for death from coronary heart disease, researchers here said. full story

http://www.medpagetoday.com/Cardiology/CoronaryArteryDisease/tb/9259


Soy and Breast Cancer 2008 A diet high in soy may raise your risk of endometrial or breast cancer, both of which are estrogen sensitive cancers. If you've been diagnosed with breast cancer, use soy moderately, and don't take soy supplements, to lower your risk of recurrence. Internationally acclaimed heart expert Kilmer McCully, MD, father of the homocysteine theory of heart disease, joined other scientists and consumer advocates in asking the Food and Drug Administration (FDA) to drop the heart disease health claim for soy protein in documents filed February 19, 2008.

http://breastcancer.about.com/od/riskfactorsindetail/a/diet_bc_risk.htm

Soy Helps Relieve Hot Flashes  That soy can relieve hot flashes is an indication that soy is a very strong estrogenic like compound, something to be avoided if one has liver cysts, breast cancer risk,  risk of endometrial cancer or risk of prostate cancer. Recent studies show that soy can contribute to or cause heart disease, including endothelial damage (especially in women), heart arrhythmias and cardiomyopathy, an increasingly prevalent condition that affects 1 in 500 Americans. The mechanism by which soy might lower cholesterol could cause endocrine disruption, diminished humoral immunity and cancer development. Soy can cause, contribute to and accelerate the growth of cancer, particularly breast cancer.

Mary Enig is a research dietician from the Price-Pottenger Foundation. Here is what she has to say about soy:

http://www.soyonlineservice.co.nz/downloads/soymyths.pdf


Isoflavones--safe food additives or dangerous drugs? 2007  [Soy] The following question arises for the clinician: Why should soy or red clover products containing isoflavone be recommended, if the positive effects are only negligible but the adverse effects serious?

http://www.ncbi.nlm.nih.gov/pubmed/17604235?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


Lycopene and other carotenoids inhibit estrogenic activity of 17beta-estradiol and genistein in cancer cells 2007   Genistein, the phytoestrogen mainly found in soy, also shows significant estrogenic activity when tested at concentrations found in human blood. The aim of this study was to determine whether carotenoids inhibit signaling of steroidal estrogen and phytoestrogen which could explain their cancer preventive activity. These results suggest that dietary carotenoids inhibit estrogen signaling of both 17beta-estradiol and genistein, and attenuate their deleterious effect in hormone-dependent malignancies.

http://www.ncbi.nlm.nih.gov/pubmed/17051425?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

The above suggests that soy and carotenoids might interact to prevent hormone receptors from signaling growth. . .


Coronary vasomotor and blood flow responses to isoflavone-intact soy protein in subjects with coronary heart disease or risk factors for coronary heart disease 2008.  Our results suggest that short-term consumption of isoflavone-intact soy protein is neither harmful nor beneficial to the coronary circulation of humans with CHD or risk factors for CHD. These data are consistent with recent cautions placed on the purported health benefits of plant sterols. 

http://www.ncbi.nlm.nih.gov/pubmed/18442357?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


Not all soy products are created equal: caution needed in interpretation of research results 2004. the primary soybean isoflavone, genistein, has received the most attention. Because consumers are becoming increasingly confused by the often conflicting dietary messages, a balanced and accurate view of the risks and benefits of soy foods and soy food components is essential. soy2.pdf

http://www.ncbi.nlm.nih.gov/pubmed/15113977?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


Dietary genistein negates the inhibitory effect of tamoxifen on growth of estrogen-dependent human breast cancer (MCF-7) cells implanted in athymic mice. 2002  Caution is warranted for postmenopausal women consuming dietary genistein while on TAM therapy for E-responsive breast cancer. soy3.pdf

http://www.ncbi.nlm.nih.gov/pubmed/11980635?ordinalpos=9&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


Physiologically achievable concentrations of genistein enhance telomerase activity in prostate cancer cells   2007

Although it is generally known that the phytoestrogen, genistein, has telomerase-repressing and anti-proliferative effects on various cancer cells at pharmacological concentrations, we report here that physiologically achievable concentrations of genistein enhance telomerase activity, the proliferation of human prostate cancer cells and tumor growth in the transgenic adenocarcinoma mouse prostate model.

http://www.ncbi.nlm.nih.gov/pubmed/17615260?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


Tofu plants may use aluminum pipes in Hawaii   Hawaii that found that men were more likely to have cognitive impairment or Alzheimer's disease if they ate tofu more than twice a week.

Bill Harris, a vegan MD who lives in Hawaii, strongly suspects that if the results of the Hawaii "brain-aging" study turn out to be valid, it may be that aluminum -- used in the refining of some soy products in Hawaii -- is the actual culprit.  Harris went out and had soy products from Hawaii tested against soy products from the mainland. He had a lab do the tests and paid for them himself. The lab found the levels of aluminum in the Hawaii products to be significantly higher. 

http://www.alkalizeforhealth.net/Lsoy.htm


A General Article about Harm from Soy. Soy has the highest percentage of  contamination by pesticides of any of the foods we eat. Japanese, and Asians in general, have much higher rates of other types of cancer, particularly cancer of the esophagus, stomach, liver and pancreas.(8) Asians throughout the world also have high rates of thyroid cancer.(9) The logic which links low rates of reproductive cancers to soy consumption requires attribution of high rates of thyroid and digestive cancers to the same foods, particularly as soy causes these types of cancers in laboratory rats. Acid washing in aluminum tanks leaches high levels of aluminum into the final product. As a result, soy-based formula also has over 1000% more aluminum than conventional milk based formulas.

http://www.healingdaily.com/detoxification-diet/soy.htm


If any benefit is obtained from eating soy,  in populations where soy was never eaten, then taking  caffeine: coffee, tea, chocolate negates this effect, also acidophilus contributes to this (yogurt).


I noticed that soy made my liver cysts grow. It is for this reason I first began avoiding soy. Since then I have many articles speaking against soy. The one that makes the most sense is that Monsanto genetically modified the soy bean to withstand a ton of roundup herbicide and the soy plant still stands. When asked by the European Union to please put this soy aside so individuals might have a choice on which soy to eat, the USA boldly refused. Soybeans that are GM modified proliferate much more quickly than non GM soy. Soy is a potent estrogen mimicker. When combined with another estrogen disruptor it can become a super estrogen disruptor i.e. roundup by monsanto or clover honey, one of the most common forms of honey sold in the USA.


Soy makes 

1. liver cysts grow

2. interferes with thyroid functioning

3. estrogen disruptor

4. Phytoestrogens  disrupt endocrine function and are potent antithyroid agents are present in vast quantities in soy, including the potentially devastating isoflavone Genistein

5. creates sterility by causing male infants testicles not to descend

6. increases the risk of developing breast cancer

7. increases risk for prostate cancer

8. soy is among the top ten most allergic foods

9. soy is said to possibly lower cholesterol but perhaps the mechanism is by soy's effect on the thyroid gland. 





http://www.pkdiet.com 

On the left is a button that says Diet Recipes. Clicking this  will take you to a recipe navigation page. At the top row in the middle is a pulldown menu that says Foods. Selecting soy from the pulldown menu  will take you to:

http://pkdiet.com/recipeiweb/recipe/Soy.html



Some notes from some older soy articles.

A study from Cornell University, published in the Journal of the American College of Nutrition, 1986, which found that children who develop diabetes mellitus were twice as likely to have been fed soy.

A November 1994 warning published in Pediatrics in which the Nutrition Committee of the American Academy of Pediatrics advised against the use of soy formulas due to the diabetes risk. These warnings have been neglected ever since it was reported that the AAP accepted a multi-dollar donation from the Infant Formula Council for their new headquarters building outside Chicago.

A 1994 article by Lonnerdal published in Acta Paediatr summarizing the reduced bioavailability of trace minerals due to high phytic acid content in soy infant formula; and high levels of manganese in soy formula compared to cows milk formula and breast milk. Excessive intake of manganese is linked to problems with the central nervous system.

A 1996 report published in the German magazine Klin Padiatr describing the development of hypocalcemic tetany in an infant fed soy formula.

Two 1997 studies published in Nutrition and Cancer. One found that phytoestrogens at levels close to probable levels in humans stimulate cellular changes leading to breast cancer; the other found that dietary soy suppressed enzymes protective of breast cancer in mice.

A 1998 study published in the American Journal of Clinical Nutritionfurther confirming that soy-protein supplementation stimulates cell proliferation in human breast tissue.

A 1998 study published in Cancer Research which found that dietary genistein enhances the growth of mammary gland tumors in mice.

A 1998 study by Nagata and others published in the Journal of Nutritionwhich gives daily consumption of tofu in Japan's Gifu prefecture as less than 1 gram per day.

A 1998 study published in Toxicology and Industrial Health indicating the phytoestrogens are potential endocrine disrupters in males.

A March 12, 1999 Daily Express article with the headline "Soy Allergy/Adverse Effect Rates Skyrocket - Monsanto's Roundup-Ready Soy Blamed"

A 1999 study at the Clinical Research Center at MIT, published in theProceedings of the Annual Meeting of the Pacific Coast Reproductive Society which found that estrogens in soy had no effect on menopausal symptoms such as hot flashes and night sweats.

May 1999 and June 2000 studies published in Brain Research indicating that phytoestrogens have adverse affects on brain chemistry.

An April 2000 study published in Proceedings of the National Academy of Science which found that flavonoids, especially genistein, can cross the placenta and induce cell changes that lead to infant leukemia.

An article published in Nutrition and Cancer 2000 which found lower testosterone levels and higher estrogen levels in Japanese men who consumed higher levels of soy foods.

Publication in the British Journal of Urology, January 2000, of the study showing a five-time greater risk of delivering a boy with hypospadias, a birth defect of the penis, in mothers who ate a vegetarian diet during pregnancy. The researchers attributed high rates of the birth defect to phytoestrogens in soy products.

An April 2000 study published in Carcinogenesis found that soy feeding stimulated the growth of rat thyroid with iodine deficiency, partly through a pituitary-dependent pathway.

A June 2000 article in American Journal of Cardiology which found that soy had no impact on lipid levels in healthy postmenopausal women

Evidence that disturbing results were omitted from a 1994 study presented to the FDA during the approval process for Roundup Ready Soybeans. Researchers found that raw Roundup Ready meal contained 27 percent more trypsin inhibitor and toasted Roundup Ready meal contained 18 percent more trypsin inhibitor compared to non-genetically manipulated controls.




 

Soy