CAFFEINE - Decaffeinated Coffee causes rise in cholesterol LDL (1989)

CAFFEINE - Lowers bone density Increases excretion of calcium and minerals for 3 hours (Massey 1993)

CAFFEINE - Raises Blood Pressure Chronic Caffeine consumption exacerbates hypertension in PKD rats (Tanner 2001)

CAFFEINE - increases PKD cysts (Grantham 2002)

CAFFEINE - vascular phenotype in PKD (Torres 2003)

CAFFEINE - increases urinary excretion of calcium (Massey 2004)

CAFFEINE - increases stone formation (Massey 2004)

CAFFEINE - raises blood pressure in women. (2006)

CAFFEINE - Decaffeinated May Be Anything But

CAFFEINE - alters cardiomyocytes signaling LVH, loss of this regulation of RyR2, as occurs when PC2 is mutated, results in altered Ca2 signaling in the heart. Mutations in polycystin 2 cause PKD.(Somlo 2007)