Octreotide, sandostatin LAR, is a somatostatin analogue. It is the first medication in clinical trials for polycystic liver disease. This long acting form of somatostatin is manufactured by Novartis. It has been used for acromegaly, carcinoid, and other rare endocrine tumors.

The very first clinical trial with octreotide LAR was undertaken in Bergamo, Italy at the Mario Negri Center. The Mario Negri Center completed a small Somatostatin trial with 12 patients that determined Octreotide LAR to be safe and reduced cystic kidneys. One participant withdrew from non symptomatic gall stones. Another withdrew from asthenia (Weakness. Lack of energy and strength. Loss of strength.)
There is a current ongoing octreotide clinical trial (yet to be completed) at the Mayo Clinic in Rochester Minnesota USA with 42 participants to determine if long acting injectable octreotide (given once every 28 days) will be useful in reducing severe polycystic liver disease. This last participant inPhase 1 years one and two clinical trial finished April 2010.
A trial in the Netherlands using an analogue of sandostatin (octreotide, lanreotide) is finished.
A third trial in Italy it to determine if octreotide reduces liver cysts. Choose an article about octreotide from the pull down menu below. Somatostatin, octreotide, lanreotide, all similar drugs with different names are all growth hormone inhibitors. Researchers from Spain, scanned the surface of liver cysts with an electron microscope and discovered that the surface contained: hormone receptors, insulin growth hormone receptors and growth hormone receptors. Octreotide inhibits hormones including insulin hormone, growth hormone; and hormones like estrogen.

-- select OCTREOTIDE article -- OCTREOTIDE Inhibits Cholangiocyte OCTREOTIDE Trial Italy OCTREOTIDE Italy reduces kidney cysts OCTREOTIDE Electron Microscope OCTREOTIDE Electron Microscope:abstract OCTREOTIDE analogues reduce liver vol OCTREOTIDE Trial Mayo OCTREOTIDE Trial Netherlands Belgium OCTREOTIDE use in Acromegaly OCTREOTIDE acromegaly articles OCTREOTIDE prescribing info OCTREOTIDE more prescribing info OCTREOTIDE how to prepare OCTREOTIDE somatostatin analogue OCTREOTIDE from wikipedia OCTREOTIDE cholangiocytes proliferate OCTREOTIDE FSH increases cholangiocytes OCTREOTIDE Uses Grantham OCTREOTIDE Uses Hogan OCTREOTIDE Uses: obesity OCTREOTIDE Uses: ascites TPN OCTREOTIDE Uses: breast cancer OCTREOTIDE Uses: endocrine tumor OCTREOTIDE Uses: reduces portal pressure OCTREOTIDE Uses: acromegaly OCTREOTIDE implant acromegaly OCTREOTIDE Netherlands Belgium subc OCTREOTIDE Works imitating somatostatin OCTREOTIDE Lanreotide OCTREOTIDE - Lanreotide Autogel OCTREOTIDE - vapreotide

A cholangiocyte article gives a good reason to avoid hormones, false hormones, estrogen receptors, xenoestrogens, especially with polycystic livers. To read more about xenoestrogens click here.