PKD Articles - Blood Pressure Articles

Salt restriction is an effective means of maintaining low blood pressure. A retrospective study was done between (2) dialysis centers. Those who used salt restriction had a lower incidence of left ventricular hypertrophy, fewer episodes of low blood pressure while on dialysis, and lower body weights. A recent article concludes in older individuals that perhaps colder weather contributes to high blood pressure. Shorter sleep duration predicted higher blood pressure, adverse changes in blood pressure, and an increased risk of hypertension over a five-year period.




High blood pressure is the most common kidney complication in ADPKD occurring in 60 percent of individuals with normal renal function. Blood pressure elevations are associated with a faster rate of decline in kidney functioning. Activation of the renin-angiotensin-aldosterone system plays an important role in high blood pressure associated with PKD Polycystic Kidney Disease. Preliminary results from long-term studies suggest that angiotensin converting enzyme inhibition, in contrast to conventional diuretic therapy, may be beneficial in preventing progression to kidney failure with PKD Polycystic Kidney Disease.


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