More PLDiet
More Liver Diet
Plant Based Alkaline Diet
Neutral Protein 0.6 grams/kilogram
1200 mg sodium
4 Liters water or twice your daily output
Low in Fat
Food Restriction
AVOID For PLD Polycystic Liver Disease (no matter the diet)
Alcohol
Ammonia
Artificial Sweeteners (stevia is included)
Bleach
Chemicals
dry clean chemicals
dry cleaned clothing
hair chemicals
hair dye
nail chemicals
Fish, especially oily fish & fish oil
Flaxseed
Hormones
Hormone disruptors (walls of liver cysts contains hormone receptors)
Liver toxins
Oats contains Roundup®
Oily fish, fish oil
Perfumes & scents all go directly to liver.Oily fish, fish oil
Pickles
Rice & products contains arsenic
Sugars
Sweeteners
Vinegars
Wheat contains many chemicals
Yeast
Xenoestrogens
HELPS PLD Polycystic Liver Disease (no matter the diet)
Spelt is the one grain that has not been modified over the years
Lemon water
Hot water with fresh lemon juice
Saffron tea
Why an alkaline diet?
Here are some alkaline clinical trials including the first ever 2010 alkaline clinical trial for kidney functioning looking at how alkalinity improved kidney functioning; alkalinizing helped preserve GFR. This study demonstrates that sodium citrate may ameliorate kidney injury in Chronic Kidney Disease patients not on dialysis. The day has come when there is evidence in humans that alkaline treatment lowers urinary endothelin levels. Increased endothelin may be part of the mechanism whereby acidosis hastens Chronic Kidney Disease progression.
Symptoms Low Potassium High Potassium
Potassium citrate improves renal functioning
Citrate therapy for PKD in rats
Bio of G. Tanner PhD researcher
2010 Alkaline Clinical Trials
2010 Alkaline Clinical Trial Improves GFR
2010 Alkaline Clinical Trials Improves Bone Density
Calcium supplements helps bones but may weaken heart
Why a plant based diet?
Most plants are alkaline. Most meats are acidic forming. When we eat animal proteins this increases stomach acidity. This stimulates the release of secretin. Secretin release causes liver cysts to expand and grow.
How to calculate neutral protein?
Calculate neutral protein: Neutral protein has been calculated to be 0.6 grams of protein per kilogram of body weight. To calculate your own amount of protein take your body weight and convert it from pounds to kilograms then multiply your kilogram weight by 0.6. This will give you your daily neutral protein intake. For instance if one weighs 110 pounds, divide 110 by 2.2. This will give 50 kilograms. Multiply 50 kilograms by 0.6. This gives 30 grams of protein eaten daily will give a 110 pound person a neutral protein intake. Neutral protein is what goes in, comes out without any excess poundage to be added to the body. Body weight in pounds / divided by 2.2. This value x multiplied by .6 gives neutral protein intake.
Why low sodium?
Himalayan pink salt - solé: High salt intake contributes to the progression of cystic organs, according to the CRISP Study. Lowering dietary sodium intake and elevating good HDL cholesterol are potentially modifiable traits that can positively contribute to PKD symptom expression.
Why water?
Water: Part of the job of the liver is to detoxify and metabolize body wastes converting this to a water-y compound to be eventually released through the kidneys. Eating animal products, or the equivalent of a 20% animal based protein diet, increases levels of certain liver enzymes. This further breaks down any circulating liver toxins to an even more toxic compound. It is this secondary compound that can be harmful to a cystic liver. Water helps dilute these by-products of liver metabolism. A cystic liver may enlarge greatly; however it is rare for a PLD liver to fail; nevertheless, the metabolism of estrogen can become greatly impaired through a cystic liver. These estrogen by-products contribute greatly to expanding a polycystic liver.
water study:
"These results support the need for a larger study to evaluate the effect of chronic water loading on ADPKD progression."
Why no caffeine?
Read about the harmful effect of caffeine and de-caf drinks upon cystic organs and a bit more on the dangers of caffeine.
| De-caf anything but | Harmful effects coffee | Caffeine in Guarana |
| Caffeine articles | Chocolate harm | Avoid tea |
| Magnesium | Avoid Cleavers | Caffeine Plants |
Why no hormones?
Cholangiocytes. The liver has two types of cells: cholangiocytes and hepatocytes. We have to establish that Polycystic Liver cysts only form from Liver cholangiocytes cells. Anything that increases cholagiocytes will increase PLD liver cysts. According to the cholangiocyte article, "Cholangiocytes are involved in both the normal developmental and pathological development of PLD Polycystic Liver Disease."
Electron Microscope view of liver cyst walls. - The Italians looked at liver cyst walls with an electron microscope. Through the electron microscope it was determined that within liver cyst walls there are hormone receptors; insulin receptors; growth hormone receptors all hormones can trigger liver cyst growth. All different types of hormones can trigger liver cyst growth. For this reason severe PLD'rs are urged not to take any hormones. Some cannot even use any creams, such as testosterone cream or prednisone creams, injections or steroids.
Cholangiociliopathies: genetics, molecular mechanisms and potential therapies. "Polycystic Liver Disease may be classified as cholangiociliopathies. In cystic cholangiocytes, over expression of ion transporters and water channels facilitates fluid secretion into the cystic lumen, and growth factors, estrogens and cytokines promote cholangiocyte proliferation." In other words, hormones cause liver cysts to fill with fluid and expand.
Follicle-stimulating hormone causes an increase in cholangiocytes. Liver cysts are only formed from cholangiocytes. Liver cysts cannot be formed from other liver cells such as hepatocytes. If follicle stimulating hormone causes an increase in cholangiocytes, this increase in our cholangiocytes, leads to the development of more liver cysts.
Histamine—Cholangiocytes increase in response to histamine receptor stimulation. This is another reason to avoid the top 10 allergic foods. Cholangiocytes proliferate in response to H1 histamine receptor stimulation and liver cysts respond to this increase in cholangiocytes.
The Top 10 Allergenic Foods —one reason to avoid allergic foods is allergic foods are capable of raising blood pressure as well as releasing histamines. The release of histamines leads to an increase in liver cholangiocytes which can create more liver cysts.
Wheat
Soy
Shellfish
Fish
Tree Nuts
Peanut
Eggs
Milk
These above eight foods are the notorious big eight list. They account for nearly 90% of food-related allergic reactions in the United States. Allergenic foods cause the release of histamine. Histamine release stimulates liver cyst growth. Rounding out the top ten food allergies are nine and ten: sesame and celery.
SesameCelery
Estrogens —stimulate the secretion of different growth factors in proliferating cholangiocytes. Estrogens and the pathophysiology of the biliary tree.
False estrogens, xenoestrogens, endocrine disruptors are to be avoided. The body thinks their similar molecular structure is true estrogen. These endocrine disruptors are incorporated into the body as estrogen. Because liver cysts contain estrogen receptors on their cell walls, PLD liver cyst receptors take all forms of false estrogens and utilize them to stimulate liver cyst growth and liver size. From amongst our mutual PLD experiences, we have gathered this information. Let us know about your experience.