"Until recently, patients on dialysis with low serum albumin levels were characterized as suffering from protein malnutrition suggesting that the cause of this malady was due to an inadequate intake of protein. In fact, these patients tend to suffer from a wasting syndrome similar to cachexia commonly associated with inflammation in which there is loss of lean body mass and fat mass is underutilized. . . . [a positive change] can be promoted by the addition of protein of high biological value that is rich in leucine . ."
Leucine appears to be the main essential amino acid responsible for protein synthesis. It is the only amino acid that can stimulate protein synthesis alone. Because older people are resistant to the anabolic effects of amino acids, researchers investigated what would happen if they bumped up the leucine content from the original 1.7 grams to 2.8 grams in a seven-gram mixture. They found that older people could then stimulate protein synthesis to the same extent as young people. Middle aged men gain muscle mass by taking leucine. Research also shows that there are no differences in the building of muscle tissue between younger and older people at a dose of 15 grams of essential aminos.
For failing kidneys perhaps another suggestion might be to ask your doctor about trying the recommendations in Mackenzie Walser MD's book; this outlines his recommendations for declining kidney functioning. It is called Coping with Kidney Disease. In addition to dropping the daily protein to 0.3 grams/kilogram, Dr. Walser recommends supplementing with amino acids specifically designed for kidney patients. The formula is produced by Calwood.
Leucine is found in chia seeds, garbanzo beans, chickpeas, brown rice, nuts, lentils, sesame seeds, hummus, beans, legumes, egg yolk, beef tea, cottage cheese, flat white fish. It can also be purchased as a powder to sprinkle in smoothies. If you happen to have polycystic liver cysts, it is best to avoid *sesame seeds as they contain large amounts of phytoestrogens. With PKD limit fish and cottage cheese.
|Leucine - A Few Food Sources of Leucine||grams/100 gm|
|Lentils cooked or sprouted||2.03|
|Cowpea, catjang, mature seeds, raw||1.83|
|Beef, tea round, top round, select, raw||1.76|
|Nuts, almonds soaked for several hours to diminish phytates||1.49|
|Egg, yolk, raw, fresh||1.40|
|Chickpeas, bengal gram, garbanzo beans, raw||1.37|
|Sesame seeds, tahini, *avoid w/PLD *||1.36|
|Snap beans, green, raw||0.11|