AlkaliZERS

Finally a 2010 scientific study clinical trial, that shows alkalinity slows down kidney failure.
Alkalinity holds the key for longevity. The scientific evidence for this has come through the detailed work of PKD researchers, George and Judy Tanner. It is through their research that we have received verification of our own empirical alkaline experiences. These two brilliant PKD researchers have opened the door for the possibility that alkaline changes could maintain the health of our cystic organs, perhaps for a lifetime. The earlier this is begun, the better are the results. We are grateful for their potassium citrate research  [K Citrate] in the PKD model. It is through the Tanners' painstakingly precise measurements and experiments that we have conclusive proof that alkalizers such as potassium citrate, are tremendously helpful in slowing down the progression of polycystic kidney disease.

Early in 1994, Dr. Torres searched out alkalinity in the PKD model. He used baking soda or sodium bicarb. The PKD model did improve however they all developed kidney stones. By testing with ammonia, the conclusion was that acidity worsens PKD. Newly found alkaline knowledge has paved the path that our greatest benefit can be achieved through alkalinity alone. From research by the Tanners on Potassium Citrate they found that citrate is helpful and potassium is also helpful, however, alkalinity provides the most substantial likelihood of achieving PKD cystic organ health.

Potassium citrate and sodium citrate are equally effective alkalizers. Calcium citrate is less so. With these citrate salts, the citrate molecule flies off and is utilized by the kidney for energy. An alkaline diet alone can achieve alkalinity. For some, supplementation with Potassium Citrate may be required to help regulate a constant alkalinity. Potassium Citrate supplements requires a physician's input to carefully monitor subtle changes in our serum potassium levels. Without this precaution, potassium levels can become dangerously high, and even life-threatening. Perhaps someday, individuals with PKD will be able to self-monitor their potassium levels much like diabetics monitor blood sugar. Get a physician's expertise help and familiarize yourself with high potassium symptoms and low potassium symptoms. If you do not feel well, go immediately to the emergency room or urgent care center and get your potassium level checked

Sodium Bicarbonate tablets is an old reliable alkalizer, used for many years, to treat chronic kidney disease.  Many nephrologists continue to prescribe sodium bicarb, also known as baking soda, to individuals late in PKD, unaware that this can promote a higher incidence of kidney stones for PKD'rs. Due to the inherent nature of PKD, unfortunately sodium bicarbonate increases kidney stone formation. Individuals with PKD kidneys have a 30% greater chance for developing kidney stones. Unlike citrate salts, where the citrate is utilized for energy, the bicarbonate ion spins off and forms a common kidney stone compound – calcium carbonate, the most common PKD kidney stone. Download a printable list of low and high potassium symptoms.

HIGH POTASSIUM                                                                                                                                                                   LOW POTASSIUM
Stomach Cramps                                                                                                                                                                       Cramping & Muscle weakness
Intestinal Cramps                                                                                                                                                                       Fatigue
Weakness Nausea                                                                                                                                                                     Confusion
Generalized Fatigue                                                                                                                                                                  Difficulties with muscle coordination
Paralysis                                                                                                                                                                                    Irregular heartbeat
Palpitations                                                                                                                                                                                Heart failure
Numbness
Burning / tingling
Slow pulse
Mental Confusion
Tiredness
Nausea
EKG changes
Irregular heartbeat
Sudden death

Nettle non-alcoholic extract is another alkalizer. It lowers uric acid. Nettle is high in potassium. Some have tried (2) two drops in a cup of warm water following each meal to keep themselves alkaline. Urtica dioica L. and Urtica urens L., (stinging nettles) are other names for nettle. Urtica semen is nettle that is derived solely from the seed.

Colchicine has been shown in the PKD model to decrease cyst growth.

Foods that are potent alkalizers:
Nettle extract [non-alcoholic]
Lemon juice
Melon juice
Orange juice
Cabbage juice
Barley and other cereal grass juices i.e., spelt grass juice, wheat grass juice
Parsley juice
Watercress and field cress

Finally a scientific study with control subjects, that shows clearly that alkalinity slows down kidney failure.
ALKALINE FOOD LIST

KIDNEY ALKALINE FOOD LIST

LIVER ALKALINE FOOD LIST

and for a printable liver list
ENJOY THESE FOODS

ENJOY THESE ALSO

AVOID THESE FOODS

AVOID THESE ALSO

BETTER ANIMAL PROTEIN CHOICES

Amelioration of metabolic acidosis in patients with low GFR reduced kidney endothelin production and kidney injury, and better preserved GFR.
A paper published in Kidney International (Phisitkul et al., vol. 77, Apr. 2010, pp. 617-623), alkalinizing helped improved kidney functioning.

Kidney Int. 2010 Apr;77(7):617-23. Epub 2010 Jan 13.

Phisitkul S, Khanna A, Simoni J, Broglio K, Sheather S, Rajab MH, Wesson DE.
Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.
Comment in:
Kidney Int. 2010 Apr;77(7):567-9.

Metabolic acidosis often accompanies low glomerular filtration rate and induces secretion of endothelin, which in turn might mediate kidney injury. Here we tested whether treatment of metabolic acidosis in patients with low glomerular filtration rate reduced the progression of kidney disease. Fifty-nine patients with hypertensive nephropathy and metabolic acidosis had their blood pressure reduced with regimens that included angiotensin-converting enzyme inhibition. Thirty patients were then prescribed sodium citrate, and the remaining 29, unable or unwilling to take sodium citrate, served as controls. All were followed for 24 months with maintenance of their blood pressure reduction. Urine endothelin-1 excretion, a surrogate of kidney endothelin production, and N-acetyl-β-D-glucosaminidase, a marker of kidney tubulointerstitial injury, were each significantly lower, while the rate of estimated glomerular filtration rate decline was significantly slower. The estimated glomerular filtration rate was statistically higher after 24 months of sodium citrate treatment compared to the control group. Hence it appears that sodium citrate is an effective kidney-protective adjunct to blood pressure reduction and angiotensin-converting enzyme inhibition.

A basic approach to CKD.
Kidney Int. 2010 Apr;77(7):567-9.
Simon EE, Hamm LL.
Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana 70112, USA.
Comment on:
Kidney Int. 2010 Apr;77(7):617-23.

Metabolic acidosis often complicates chronic kidney disease (CKD) and adversely affects bone, nutrition, and metabolism. Phisitkul et al. demonstrate that sodium citrate may ameliorate kidney injury in CKD patients not on dialysis. Further, they provide evidence in humans that treatment lowers urinary endothelin levels, and hence increased endothelin may be part of the mechanism whereby acidosis hastens CKD progression.

And for those with kidney stones, here is an article

J Phys Chem B. 2009 Jul 16;113(28):9547-50.
The complexon-renal stone interaction: solubility and electronic microscopy studies.
Kustov AV, Berezin BD, Trostin VN.
Institute of Solution Chemistry of Russian Academy of Sciences, Ivanovo, Russian Federation. kustov@isuct.ru

We have studied how complex formation between calcium and ethylenediaminetetraacetate or citrate ions influences the surface texture and the size of passed oxalate-phosphate renal stones. The four hour concrement treatment by sodium citrate or ethylenediaminetetraacetate aqueous solutions strongly affects the stone texture and provides a mass loss of 6-15%. We have found a significant decrease of the calcium and phosphor content on a concrement surface and formation of appreciable cracks. Our results do indicate that the Ca-complexon interaction can be effectively applied for disrupting some types of renal stones and, especially, residual concrements, which frequently occurs after a surgical operation or an extracorporeal shock-wave lithotripsy. This study provides an additional quantitative physicochemical basis for this slightly invasive therapy.

Atubular glomeruli in a rat model of polycystic kidney disease.
Tanner GA. Tielker MA, Connors BA, Phillips CL, Tanner JA, Evan AP.
Kidney Int. 2002 Dec;62(6):1947-57.
PMID: 12427119 [PubMed - indexed for MEDLINE]Free Article

Citrate therapy for polycystic kidney disease in rats.
Tanner GA. Tanner JA.
Kidney Int. 2000 Nov;58(5):1859-69.
PMID: 11044205 [PubMed - indexed for MEDLINE]Free Article

Potassium citrate/citric acid intake improves renal function in rats with polycystic kidney disease.
Tanner GA.
J Am Soc Nephrol. 1998 Jul;9(7):1242-8.
PMID: 9644634 [PubMed - indexed for MEDLINE]Free Article

ALKALINE DIET information try here. Scroll through the list on your left of submenus to read more foods specifically to help diminish liver cysts; kidney cysts; to gain weight; to lose weight; what to eat when traveling; and more.

ALKALINITY information try here. Scroll through the list of submenus on your left to read about how to test your urinary pH, nettle extract, colchicine, potassium citrate and more.

FOODS, for more detail try here. Select from the different food pictures by clicking on the sliding doors or choose from the pull down menu.