Leucine
Enjoy Leucine
Getting to the Meat of the Matter: Beyond Protein Supplementation in Maintenance Dialysis
Renal Division, Dept of Medicine, Emory University School of Medicine, Atlanta, Georgia.
"Until recently, patients on dialysis with low serum albumin levels were characterized as suffering from protein malnutrition suggesting that the cause of this malady was due to an inadequate intake of protein. In fact, these patients tend to suffer from a wasting syndrome similar to cachexia commonly associated with inflammation in which there is loss of lean body mass and fat mass is underutilized. . . . [a positive change] can be promoted by the addition of protein of high biological value that is rich in leucine . ."
Protein Synthesis
Leucine appears to be the main essential amino acid responsible for protein synthesis. It is the only amino acid that can stimulate protein synthesis alone.
Middle aged men gain muscle mass by taking leucine. Leucine appears to be the main essential amino acid responsible for protein synthesis. It is the only amino acid that can stimulate protein synthesis alone. Because older people are resistant to the anabolic effects of amino acids, researchers investigated what would happen if they bumped up the leucine content from the original 1.7 grams to 2.8 grams in a seven-gram mixture. They found that older people could then stimulate protein synthesis to the same extent as young people. Research showed that there are no differences in building of muscle tissue between younger and older people at a dose of 15 grams of essential aminos. Because older people are resistant to the anabolic effects of amino acids, researchers investigated what would happen if they bumped up the leucine taken in from the original 1.7 grams to 2.8 grams. They found that the older people could stimulate protein synthesis to the same extent as young people.
What Can Leucine Do?
↑ serum albumin
Responsible protein synthesis
Builds muscle mass in middle aged men
Teenage girls sprint faster
Dialysis patients corrects low serum albumin
Corrects lipids
Modulates intestinal flora
Regulates blood sugar
Provides omega 3's
lowers appetite
digestive tract support
Failing Kidneys
For failing kidneys perhaps another suggestion might be to ask your doctor about trying the recommendations of Mackenzie Walser MD book. The late Dr. Mackenzie Walser Johns Hopkins University Medical Center wrote a book outlining his recommendations for declining kidney functioning called Coping with Kidney Disease. In addition to dropping the daily protein to 0.3 grams/kilogram, Dr. Walser recommends supplementing with amino acids specifically designed for kidney patients. The formula is produced by Calwood.
Leucine reduces appetite and contains omega 3's. Garbanzo beans are not a fatty food, they do contain valuable amounts of polyunsaturated fatty acids, including alpha-linolenic acid (ALA), the body's omega-3 fatty acid from which all other omega-3 fats are made. There are about 70-80 milligrams of alpha-linolenic acid (ALA) in every cup of garbanzo beans.Leucine is found in chia seeds, garbanzo beans, chickpeas, brown rice, nuts, lentils, sesame seeds, hummus, beans, legumes, egg yolk, beef tea, cottage cheese, flat white fish. It can also be purchased as a powder to sprinkle in smoothies. If you happen to have polycystic liver cysts, it is best to avoid *sesame seeds as they contain large amounts of phytoestrogens. With PKD limit fish and cottage cheese.
Leucine - A Few Food Sources of Leucine | grams/100 gm |
---|---|
Lentils cooked or sprouted | 2.03 |
Cowpea, catjang, mature seeds, raw | 1.83 |
Beef, tea round, top round, select, raw | 1.76 |
Nuts, almonds soaked for several hours to diminish phytates | 1.49 |
Chickpeas, bengal gram, garbanzo beans, raw | 1.37 |
Sesame seeds, tahini, avoid w/PLD | 1.36 |
Chia Seeds | 1.29 |
Hummus | 0.35 |
Asparagus | 0.13 |
Snap beans, green, raw | 0.11 |